Clinical investigation of compound glycyrrhizin combined with bozhi glycopeptide in treatment of erythema nodosum
10.3760/cma.j.issn.1673-4904.2014.27.017
- VernacularTitle:复方甘草酸苷联合薄芝糖肽治疗结节性红斑疗效观察
- Author:
Hehui YIN
;
Guoyang LI
- Publication Type:Journal Article
- Keywords:
Erythema nodosum;
Compound glycyrrhizin;
Bozhi glycopeptide
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(27):47-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect and safety of compound glycyrrhizin combined with bozhi glycopeptide in treatment of erythema nodosum.Methods Sixty-four patients with erythema nodosum were divided into treatment group (36 cases) and control group (28 cases) by random digits table method.The patients in treatment group were given compound glycyrrhizin 120 mg,intravenous drip,once a day;and bozhi glycopeptide 4 ml,intravenous drip,once a day.The patients in control group were given compound glycyrrhizin 120 mg,intravenous drip,once a day.The clinical efficacy and recurrence were compared between 2 groups.Results The total effective rate in treatment group was significantly higher than that in control group [86.1％ (31/36) vs.57.1％ (16/28)],there was statistical difference (P ＜ 0.05).Follow-up for 3 months,the rate of recurrence in treatment group was significantly lower than that in control group [16.1％(5/31) vs.8/16],there was statistical difference (P＜ 0.05).Conclusion Compound glycyrrhizin combined with bozhi glycopeptide can effectively control the erythema nodosum,and has no significant adverse reactions,reduces the rate of recurrence,and it is worthy of promotion and application.
