The therapeutic effect of insulin lispro mix 50/50 combined with metformin in newly diagnosed overweight/obese type 2 diabetic mellitus patients
10.3760/cma.j.issn.1673-4904.2014.19.002
- VernacularTitle:赖脯胰岛素50联合二甲双胍治疗新诊断超重/肥胖2型糖尿病的疗效分析
- Author:
Ping YANG
;
Yi WEI
- Publication Type:Journal Article
- Keywords:
Overweight;
Obsity;
Diabetes mellitus,type 2;
Insulin lispro mix 50/50;
Intensive therapy
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(19):4-6
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect and safety of insulin lispro mix 50/50 combined with mefformin in newly diagnosed overweight/obese type 2 diabetic mellitus patients.Methods Sixty-two patients with newly diagnosed overweight/obsess type 2 diabetic mellitus were randomly divided into observation group (32 cases) and control group (30 cases) by systematic sampling method.The observation group received insulin lispro mix 50/50 combined with metformin,and the control group received recombinant human insulin and insulin glargine.The therapeutic effect and safety were compared between the 2 groups.Results There were no statistical differences in the blood glucose before eating,before retiring and at mane primo 3:00 between the 2 groups (P ＞ 0.05).There were no statistical differences in the time of blood glucose standard and rate of hypoglycaemia between the 2 groups (P ＞ 0.05).Daily insulin dosage and costs in the observation group were lower than those in the control group [(0.6 ± 0.1) U/kg vs.(0.8 ± 0.1) U/kg and (15.8 ±2.1) yuan/d vs.(21.3 ±2.6) yuan/d],and there were statistical differences (P ＜0.05).Conclusion Insulin lispro mix 50/50 combined with mefformin provides a convenient,effective and safe therapy for newly diagnosed overweight/obese type 2 diabetic mellitus patients and high cost performance.
