Application of carbon nanoparticle in the axillary sentinel lymph node biopsy for breast cancer

VernacularTitle:纳米炭在乳腺癌腋窝前哨淋巴结活检中的临床应用
Author: Shuanggen LEI ; Xiaofen YU ; Chunwei XIE ; Mengying JI ; Qiumo LEI
Publication Type:Journal Article
Keywords: Breast neoplasms; Sentinel lymph node biopsy; Carbon nanoparticle
From: Chinese Journal of Postgraduates of Medicine 2014;37(26):1-3
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical effect of carbon nanoparticle in the axillary sentinel lymph node tracer of breast cancer.Methods Fifty-seven patients with breast cancer underwent lymphatic tracing with carbon nanoparticle.The carbon nanoparticle suspension was subcutaneously injected around the areola (points at 4 o'clock) and tumor surface skin at 30 min before operation.The first lymph nodes blacked were named sentinel lymph node.Then performed modified radical mastectomy,observing the application value of carbon nanoparticle.Results The detection rate of sentinel lymph node was 98.2％ (56/57).The correct,sensitive and false negative rates were 98.2％(55/56),95.2％(20/21) and 4.8％(1/21),respectively.The false positive rate was 0.Conclusions The carbon nanoparticle suspension injection subcutaneously around areola in sentinel lymph node biopsy is helpful for accurately evaluating the axillary lymph node condition.Being simple to operate,accurate positioning,dyeing time and is worth popularizing.