The prognostic risk factors of low level malignant obstructive jaundice treated with transhepatic biliary drainage
10.3760/cma.j.issn.1673-4904.2014.20.018
- VernacularTitle:低位恶性梗阻性黄疸应用介入引流治疗的预后相关危险因素分析
- Author:
Gang CHANG
;
Dong XUE
;
Xiaoyan ZHANG
;
Yuehong GONG
;
Zaibo JIANG
- Publication Type:Journal Article
- Keywords:
Jaundice,obstructive;
Risk factors;
Drainage;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(20):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prognostic risk factors of low level malignant obstructive jaundice treated with transhapetic biliary drainage.Methods The clinical data of 142 patients with low level malignant obstructive jaundice received percutaneous transhapetic biliary drainage management from January 2010 to June 2013 were retrospectively analyzed.The study parameters included gender,age,tumor type,preoperative obstructive time,preoperative infection,drainage method,Child-Pugh grade,serum total bilirubin (TBIL),albumin (ALB),serum creatinine (SCr),the postoperative declining degree of bilirubin and postoperative antineoplastic therapy.The prognostic risk factors were evaluated.Results Single variable analysis showed that preoperative infection (P =0.006),Child-Pugh grade (P =0.004),SCr (P =0.043),the postoperative declining degree of TBIL (P =0.001) and postoperative antineoplastic therapy (P =0.015) were the related factors for survival time.The further Logistic regression analysis showed that preoperative infection (OR =3.729,95％ CI 1.332-6.363,P =0.040),Child-Pugh grade ≥ 10 scores (OR =0.513,95％ CI 0.375-1.276,P =0.018) and postoperative antineoplastic therapy (OR =0.668,95％ CI 0.210-2.026,P =0.038) were the related factors for survival time.Conclusion In treating of low level malignant obstructive jaundice with transhapetic biliary drainage,the preoperative infection,Child-Pugh grade and postoperative antineoplastic therapy may be the important related factors that affect the patient's survival time,to evaluate the prognosis of these patients has important reference meaning.
