Analysis of hypopharyngeal squamous cell carcinoma of the selective neck lymph dissection of lymph nodes detected by quantitative correlation with prognosis
10.3760/cma.j.issn.1673-4904.2014.24.018
- VernacularTitle:下咽鳞状细胞癌择区颈淋巴清扫术检出淋巴结数量与预后的相关性分析
- Author:
Jing LIU
;
Zhulin CHEN
;
Jinhui LIANG
;
Duoxi MAO
;
Xianfeng CHEN
- Publication Type:Journal Article
- Keywords:
Hypopharyngeal neoplasms;
Carcinoma,squamous cell;
Neck dissection;
Lymphatic metastasis;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(24):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between the patients with hypopharyngeal squamous cell carcinoma of the selective neck lymph dissection of lymph nodes detected quantity and prognosis.Methods Retrospective analysis of the clinical data of 96 cases underwent selective dissection of cervical lymph node in patients with squamous cell carcinoma of the hypopharynx.Results All patients with unilateral selective neck dissection of lymph nodes detected a number of 19.3 ± 11.0,the number of positive lymph nodes 0.8 ± 0.6.Preoperative radiotherapy patients (43 eases) was detected in lymph nodes and the number of positive lymph nodes was 13.8 ± 7.9 and 0.2 ± 0.2,without radiotherapy patients (53 cases) of lymph nodes detected number 23.2 ± 11.9 and 1.0 ± 0.2,the comparison between the two (P ＜ 0.01).According to the number of positive lymph nodes were divided into ≤ 15 group (42 cases) and ＞ 15 group (54 cases),＞ 15 group,the overall survival rate at 3 years and 3 years disease free survival rate and neck control rate was significandy higher than that of ≤ 15 group [70.4％(38/54) vs.38.1％(16/42),61.1％(33/54) vs.33.3％ (14/42),96.3％(52/54) vs.76.2％(32/42)] (P ＜ 0.01 or ＜ 0.05).Multivariate analysis showed that lymph nodes detected a number ＞ 15 was the survival rate of the independent risk factors for overall survival in patients with and without effect (P ＜ 0.05).Conclusion Selective neck dissection of lymph nodes detected number can be used to predict prognosis in patients with squamous cell carcinoma of the hypopharynx.
