Clinical value of para-aortic lymphadenectomy in patients with cervical cancer in stage Ⅰ B2 and Ⅱ A2
10.3760/cma.j.issn.1673-4904.2014.21.017
- VernacularTitle:Ⅰ B2、Ⅱ A2期宫颈癌根治术中联合腹主动脉旁淋巴结切除术的应用价值探讨
- Author:
Chuntong WANG
;
Yuehe LIU
;
Caixia LI
- Publication Type:Journal Article
- Keywords:
Cervical cancer;
Lymph node metastasis;
Lymphadenectomy
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(21):52-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of para-aortic lymphadenectomy in patients with cervical cancer in stage Ⅰ B2 and Ⅱ A2.Methods One hundred and six patients with cervical cancer in stage Ⅰ B2 and Ⅱ A2 were assigned into two groups:control group(55 patients,radical hysterectomy and pelvic lymphadenectomy) and study group (51 patients,radical hysterectomy,pelvic lymphadenectomy and para-aortic lymphadenectomy).Postoperative radiotherapy or chemotherapy was conducted appropriately.Intraoperative and postoperative characteristics,recurrence rate,survival rate were compared between two groups.Results In study group,the recurrence rate was 15.7 ％ (8/51),and in control group,the recurrence rate was 38.2％(21/55),there was significant difference (P ＜ 0.05).No significant difference were observed in the complication incidence [27.5％ (14/51) vs.30.9％ (17/55)],blood loss [(326.1 ± 59.1) ml vs.(316.1 ± 51.2) ml] and pelvic lymph node-positive rate [56.9％ (29/51) vs.58.2 ％ (32/55)](P ＞ 0.05).The incidence of para-aortic lymph node metastasis was 17.6 ％ (9/51).Positive correlation was observed between the number of the pelvic lymph node metastasis and para-aortic lymph node metastasis (P ＜ 0.01).Conclusions In cervical cancer,the number of the pelvic lymph node metastasis was associated with para-aortic lymph node metastasis,abdominal aortic lymphadenectomy in radical surgery for cervical cancer is safe and feasible and can improve the prognosis of the patients.
