A Case of Childhood Malignant Hyperthermia Complicated by Rhabdomyolysis.
- Author:
Bum Hee LEE
1
;
Jin Sook LEE
;
Hee Yeon CHO
;
Ju Hyung KANG
;
Hee Gyung KANG
;
Il Soo HA
;
Hae Il CHEONG
;
Yong CHOI
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. ilsooha@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Dantrolene;
General anaesthesia;
Rhabdomyolysis;
Malignant hyperthermia
- MeSH:
Anesthesia, General;
Azotemia;
Dantrolene;
Humans;
Hypertension;
Male;
Malignant Hyperthermia*;
Midazolam;
Mortality;
Myoglobinuria;
Rhabdomyolysis*;
Succinylcholine;
Tachycardia
- From:Journal of the Korean Society of Pediatric Nephrology
2003;7(2):229-233
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mortality and morbidity of malignant hyperthermia has decreased markedly by the avoidance of succinylcholine, and the earlier detection and introduction of dantrolene. We report a fourteen-year-old boy who developed malignant hyperthermia during general anesthesia. He showed the earlier clinical signs, such as elevation of end-tidal CO2, tachycardia, and hypertension. After prompt administration of dantrolene, operation was continued with profopol and midazolam. Rhabdomyolysis and myoglobinuria followed, and were managed by hydration and alkalinization of urine. Azotemia did not occur, and he was discharged without any sequelae on the 10th postoperative day.
