The effect on ovarian function after myomectomy assessed by serum anti-Mullerian hormone levels
10.3969/j.issn.1006-5725.2014.16.015
- VernacularTitle:抗苗勒管激素评价子宫肌瘤剔除术后卵巢功能的改变
- Author:
Haiying WANG
;
Jieling LIANG
;
Renli ZHANG
;
Yanlin BI
;
Huaiqin LUO
;
Zhoumei JIANG
;
Anmin WEN
- Publication Type:Journal Article
- Keywords:
Anti-Mullerian hormone;
Myomectomy;
Ovarian function
- From:
The Journal of Practical Medicine
2014;(16):2573-2575
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of this prospective study was to evaluate the changes in the ovarian reverse after myomectomy based on serum anti-Mullerian Hormone (AMH) levels. Methods This is a prospective longitudinal observational study. Serum AMH levels were measured at the baseline and 2 day , 3months after myomectomy in 35 women aging from 36 to 45years.Follicle stimulate hormone(FSH) and luteal hormone(LH) were measured at the same time. 35 women of the same age with fibroid who did not undergo operation were selected as control group. Result (1)AMH level is (1.54 ± 0.95)ng/mL,(1.18 ± 0.77)ng/mL,(1.50 ± 0.58 )ng/mL at 0 day, 2 days and 3 months after operation. AMH level decreased significantly at 2 days after operation (P < 0.05) and increased gradually 3 months after operation, but showed no significant change (P > 0.05).(2) Significant differences in the serial change of AMH levels existed at each time point between myomectomy group and control group (P <0.05). No significant differences in FSH or LH levels existed at each time point. Conclusion AMH is may be superior to FSH or LH in evaluating the changing of ovarian reverse. The study suggests that myomectomy affect the ovarian function for up to 3 months post-operatively , and hemorrhage during and after operation may decrease serum AMH levels.
