The analysis of clinical outcome of frozen-thawing embryo transfer after whole embryo cryopreservation
10.3969/j.issn.1006-5725.2014.16.017
- VernacularTitle:全胚冷冻后冻融周期移植的临床结局分析
- Author:
Pan LI
;
Hong JIANG
;
Jingjing CHEN
- Publication Type:Journal Article
- Keywords:
Whole embryos cryopreservation;
Blastocyst;
Cleavage-stage embryo;
Clinical outcomes
- From:
The Journal of Practical Medicine
2014;(16):2580-2582
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the outcomes of frozen-thawed blastocyst and cleavage embryo transfer after whole embryos cryopreservation. Methods The data of 489 IVF-ET cycles in reproductive medicine center of our hospital from September 2012 to August 2013 were analyzed retrospectively. Whole embryos cryopreservation in 214 patients were carried out with vitrification method and served as group A , 275 cycles performed fresh embryo transfer were served as group B. Then group A and group B were subdivided into group A1 (83 cycles),group A2 (131 cycles), group B1 (120 cycles)and group B2 (155 cycles)according to blastocyst transfer or cleavage-stage embryo transfer. The clinical outcomes of all groups were compared each other. Results The pregnancy rate and embryo implantation rate in group A1 were significantly higher(71.1% ,53.0%)than those in group A2, B1 and B2 (A2 group: 57.3%, 34.0%, B1group: 55.0%,42.1%, B2 group: 52.9%, 32.7%,respectively)(P<0.05). The embryo implantation rate in group B1 were higher than those in group B2 (P < 0.05). Conclusion F-ET after whole embryos freezing could significantly improve the embryo utilization rate and clinical pregnancy rate. Frozen-thawed blastocyst transfer could get better clinical outcomes than frozen-thawed cleavage-stage embryo transfer.
