Investigation on reference range of anti-mutated citrullinated vimentin antibody among healthy individuals in Northeast area of Sichuan
10.3969/j.issn.1673-4130.2014.15.014
- VernacularTitle:川东北地区健康人群抗突变型瓜氨酸波形蛋白参考范围调查
- Author:
Qiang WANG
;
Dongsheng WANG
;
Juan DU
- Publication Type:Journal Article
- Keywords:
anti-mutated citrullinated vimentin antibody;
reference range;
healthy individuals
- From:
International Journal of Laboratory Medicine
2014;(15):2000-2001
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the reference range of anti-mutated citrullinated vimentin antibody (anti-MCV ) among healthy individuals in Northeast area of Sichuan .Methods The Alegria enzyme-linked immunosorbent assay system and the matched anti-MCH reagent test kit were adopted to detect the serum anti-MCV concentration in 141 serum samples collected from healthy individuals .Results The intra-batch and inter-batch precisions and the functional sensitivity of the Alegria enzyme-linked immunosorbent assay system all met the laboratory requirements .The concentration of serum anti-MCV was 12 .10(6 .70-41 .30) U/mL in the healthy female group and 11 .10(6 .00-18 .30)U/mL in the healthy male group ,there was no statistical difference be-tween these two groups(Z= -0 .991 ,P=0 .322);the detection results of serum anti-MCV in the age groups of <50 years old and ≥50 years old had no statistical differences (Z= -0 .588 ,P= 0 .558) .The reference range of anti-MCV in the investigated healthy individuals was 0 .00-18 .14 U/mL .Conclusion The reference range of anti-MCV has no correlation with gender and age . Establishing the reference range of anti-MCV suitable for the healthy population in the local area has very important clinical applica-tion value .
