Seroepidemiological analysis of Epstein-Barr virus infection in children in Guangzhou area
10.3969/j.issn.1673-4130.2014.15.028
- VernacularTitle:广州地区儿童患者EB病毒感染分析
- Author:
Tao LIN
;
Yi CHEN
;
Guangwan LIAN
;
Huanhui CHEN
;
Xiaomin LIU
- Publication Type:Journal Article
- Keywords:
children;
Epstein-Barr virus;
infection
- From:
International Journal of Laboratory Medicine
2014;(15):2033-2034
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the Epstein-Barr virus(EBV) infection status in children .Methods The EBV infection related antibody data of the children patients in our center during 2013 were collected and performed the statistical analysis on the age ,dis-ease type and month distribution .Results Totally 7 582 children cases were detected .The total infection rate of EBVCA-IgM was 16 .97% .The positive rates of specific EBVCA-IgM in different age stages were 15 .92% in 0 - <3 years old ,22 .53% in 3 - <6 years old ,16 .69% in 6- <10 years old and 8 .30% in more than 10 years old;in EBV infection cases ,most of them were infections mononucleosis ,followed by respiratory tract infection ;March and September had the highest EBV infection rate .The positive rates of series antibodies detection of EBV were 19 .11% for EBVCA-IgM ,61 .57% for EBVCA-IgG ,53 .76% for EBNA-1-IgG and 9 .50% for EBVEA-IgG ,the proportion of the combination of positive EBVCA-IgG and positive EBNA-1-IgG was highest ,account-ing for 39 .57% .Conclusion EBV is an important infectious pathogen in children infection ;39 .57% of children are once infected by EBV in the past ;with the age increase ,the EBV infection proportion will be decreased .
