Clinical effect of desogestrel ethinylestradiol in the treatment of adolescent dysfunctional uterine bleeding

VernacularTitle:去氧孕烯炔雌醇治疗青春期功能失调性子宫出血疗效分析
Author: Xuelian HE ; Lin ZHUANG ; Xiaoyin WANG
Publication Type:Journal Article
Keywords: Functional uterine bleeding; Puberty; Desogestrel and ethinylestradiol tablets
From: Chinese Journal of Primary Medicine and Pharmacy 2014;(19):2942-2943
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical efficacy and adverse reactions of desogestrel ethinylestradiol in the treatment of dysfunctional uterine bleeding ( adolescent Dub ) .Methods 86 cases with adolescent functional bleeding were divided into the treatment group and control group ,43 cases in each group .The control group received conjugated estrogen(Premarin) treatment,the treatment group was given desogestrel ethinylestradiol treatment .The hemostatic effect and drug adverse reaction of the two groups were observed .Results The cure rate of the treatment group was 65.1%,that in the control group was 23.3%,there was significant difference between the two groups (χ2 =15.28,P<0.01).The hemostatic time of the treatment group was (33.24 ±12.85)h,which was shorter than (50.31 ± 16.32)h of the control group (t=5.39,P<0.05).The incidence rate of adverse reactions between the two groups had no significant difference (χ2 =0.49,P>0.05).Conclusion Desogestrel ethinylestradiol in the treatment of ado-lescent functional bleeding has exact curative effect ,it has low incidence of adverse reactions and better acceptance .