Correlation between body mass index and insulin dose in type 2 diabetic patients with continuous subcutaneous insulin infusion
10.3969/j.issn.1006-5725.2014.15.018
- VernacularTitle:2型糖尿病持续皮下胰岛素输注治疗起始剂量与体质指数相关性研究
- Author:
Cuige LIANG
;
Qingyu DONG
;
Wenhua DU
;
Xiaomeng LIU
;
Wenxia LI
;
Yueli WANG
;
Qian GONG
;
Zhenyu PAN
;
Guanqi GAO
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Body mass index;
Insulin dose;
Continuous subcutaneous insulin infusion
- From:
The Journal of Practical Medicine
2014;(15):2408-2410
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between BMI and insulin dose in diabetic patients after short-term continuous subcutaneous insulin infusion (CSII). Methods Three hundred patients with type 2 diabetes mellitus (T2DM) were enrolled and randomized into the normal weight (BMI < 23 kg/m2) group, overweight (BMI 23 ~ 25 kg/m2) group and obesity (BMI≥25 kg/m2) group. The metabolic and anthropometric parameters of each group were compared and the related factors which may influence insulin dose were analyzed. Results The insulin dose per weight in the overweight group or in the obesity groups was significantly lower than that in the normal weight group. Weight and BMI were negatively correlated with the insulin dose per weigh. Conclusions Differences of glycemia level , β-cell function and insulin resistance exist in Chinese type 2 diabetes patients with different BMI. The stratification of BMI should be considered before estimating the insulin dose by body weight in CSII therapy.
