Relationship between the virus content of high risk HPV and cervical intraepithelial neoplasia
10.3760/cma.j.issn.1008-6706.2014.17.003
- VernacularTitle:高危型人乳头瘤病毒含量与子宫颈癌前病变关系的研究
- Author:
Ye WANG
;
Yumei CHEN
;
Liqin PAN
;
Dan PAN
- Publication Type:Journal Article
- Keywords:
Papillomavirus infections;
Cervical intraepithelial neoplasia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(17):2567-2569
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the virus content of high risk HPV and cervical intraepithelial neoplasia(CIN).Methods 450 patients with cervical intraepithelial neoplasia (CIN) were selected as the observation group ,450 healthy women at the same time were the control group ,then the positive rate and content of the control group and observation group with different high risk HPV types were detected and compared ,then the detection results of observation group with different CIN classification were compared too ,and the relationship of the detection indexes between the CIN were analyzed by the Logistic analysis .Results The HPV DNA positive rate of observation group with different high risk types were 9.11%,6.67%,6.67%,6.67%and 6.00%,respectively,and they were all higher than those of control group (χ2 =6.871,6.240,6.240,6.240,5.871,all P<0.05),and the positive rate of patients with different CIN classification had obvious differences too ,the virus content and constitution of observation group were respectively (301.35 ±32.67) Copies/mL and 11.56%,10.22%,9.56%,and they were all obviously higher than those of control group (t=6.276,χ2 =7.132,6.915,5.878,all P<0.05),and the content of patients with different classification had obvious differences ,all P<0.05,there were all significant differences ,and the item had close relationship to CIN by the Logistic analysis .Conclusion The high risk HPV virus content of patients with cervical intraepithelial neoplasia shows abnormal state ,and which have close relationship to the disease .
