Imaging and pathological features of atypical teratoid/rhabdoid tumors in the central nervous system
10.3969/j.issn.1002-1671.2014.08.004
- VernacularTitle:中枢神经系统非典型畸胎样/横纹肌样瘤的影像与病理学研究
- Author:
Huachen ZHU
;
Jian ZHOU
;
Zhiping WANG
;
Nan ZHOU
;
Peiyi GAO
- Publication Type:Journal Article
- Keywords:
atypical teratoid/rhab doid tumor;
central nervous system;
computed tomography;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2014;(8):1263-1266
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the imaging and pathological features of atypical teratoid/rhab doid tumor (AT/RT)occur-ring in the central nervous system (CNS).Methods The CT and MRI findings of 1 6 patients with CNS AT/RT were retrospectively analyzed,and their pathological and immunohistochemical results were studied.Results There were 12 males and 4 females. Tumors located is at supratentorial in 10 and infratentorial in 6.Cystic changes in tumors were noted in 12 cases.The solid portion of tumors was isointense on T2-weighted images relative to normal brain grey matter in 9 patients.Extensive peritumoral edema was observed in 1 1 lesions.The tumors showed bandlike rim of significant enhancement in 10 cases.The incidence of hemorrhage and calcification in tumors were 43.8% and 41.7% respectively.Histopathologically,AT/RT was characterized by the presence of rhab-doid cells associated with variable components of epithelial,primitive neuroectodermal and mesenchymal differentiation.Conclusion Atypical teratoid/rhabdoid tumor is several imaging findings which are relatively specific on CT and MR images.CT and MRI may provide valuable information for pre-operation diagnosis and prognostic evaluation in patients with CNS AT/RT.
