Efficacy of chronic disease management in the treatment and quality of life for rheumatoid arthritis
10.3760/cma.j.issn.1671-7368.2014.07.007
- VernacularTitle:综合管理对类风湿关节炎患者疾病控制及生存质量的影响
- Author:
Jing ZHANG
;
Li LONG
;
Qiao ZHOU
;
Tong WU
;
Jiang SU
;
Bin ZHOU
- Publication Type:Journal Article
- Keywords:
Disease management;
Arthritis,rheumatoid
- From:
Chinese Journal of General Practitioners
2014;13(7):551-553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of chronic disease management in the treatment and quality of life for rheumatoid arthritis (RA).Methods A total of 160 patients with active RA were selected from June 2011 to August 2012 and randomly assigned into experimental and control groups (n =80 each).Based upon oral medication,the experimental group had chronic disease management for 6 months.Before and after therapy,DAS28 score,erythrocyte sedimentation rate (ESR),ACR50 and quality of life score were measured.Results The number of regular medication in experimental group was significantly more than that in the control group (68 vs.37,x2 =26.625,P =0.000).The inter-group difference of DAS28 score reduction was statistically significant (2.46 ± 1.09 vs.3.68 ± 1.65,t =1.655,P =0.002).After intervention,ESR significantly decreased in experimental group (66.09 ± 41.98 vs.21.27 ± 19.61,t =1.655,P =0.029) and the reduction of control group was not statistically significant (t =1.976,P =0.059).The number of ACR50 in experimental group was more than that in control group (60 vs.44,x2 =4.314,P =0.038).The score of life quality of experimental group increased dramatically (56.58 ± 20.24 vs.63.71 ± 18.35,t =1.655,P =0.013) and it was significantly higher than control group (63.71 ± 18.35 vs.48.76 ± 19.88,t =1.906,P =0.020).Conclusion Chronic disease management can improve the life quality and clinical indices of RA patients.Thus it may be widely applied clinically as an adjunct treatment.
