The evolution of multiple myeloma treatment strategies based on changes in effect judgment
10.3969/j.issn.1000-8179.20140928
- VernacularTitle:从疗效判断的变化看多发性骨髓瘤治疗策略的演进
- Author:
Yizhuo ZHANG
;
Yafei WANG
- Publication Type:Journal Article
- Keywords:
multiple myeloma;
definition of response;
treatment strategy
- From:
Chinese Journal of Clinical Oncology
2014;(13):827-830
- CountryChina
- Language:Chinese
-
Abstract:
Basic research and clinical research on multiple myeloma (MM) have extensively progressed, as proven by the change in the definition of complete response (CR). With improvements in laboratory technology and introduction of novel agents, CR particu-larly emphasized both micro-and macro-models. The development of CR yielded therapeutic advances in MM and vice versa. The defi-nitions of response and treatment strategies were closely connected and improved. A need exists for further detailed studies on long-term disease control, such as optimal combination of agents. Given the shortage of new drugs and the distinctiveness of health in-surance, Chinese doctors should select the best treatment projects based on real-life situation in China.