Study Progress in Apolipoprotein A-I's Gene Polymorphism and Its Relationship with Reverse Cholesterol Transport
10.11842/wst.2014.07.036
- VernacularTitle:载脂蛋白A-I基因多态性与胆固醇合成逆转关系的研究进展
- Author:
Yi ZHANG
;
Jing ZHAO
;
Siyuan PAN
- Publication Type:Journal Article
- Keywords:
Apolipoprotein A-I;
gene polymorphism;
hyperlipidemia;
reverse cholesterol transport
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(7):1649-1654
- CountryChina
- Language:Chinese
-
Abstract:
Apolipoprotein A-I (apoA-I) is a member of the apolipoprotein A family, which was discovered the earli-est. It has an important role in the regulation of lipid metabolism, which mainly includes cholesterol synthesis and transfer. Therefore, apoA-I is closely related to hyperlipidemia and atherosclerosis. Clinically, serum ApoA-I/ApoB has been used as one of the indexes of hyperlipidemia. This article reviewed the study progress in ApoA-I's gene polymorphism and its relationship with reverse cholesterol transport (RCT).