Content of Six Compounds in Urine and Feces After Intragastric Administration of Shegan Heji in Rat
10.3870/yydb.2014.08.002
- VernacularTitle:射干合剂灌胃后大鼠尿及粪便中6种成分含量
- Author:
Yuenian TANG
;
Jian ZHANG
;
Xiaotong LU
;
Ting CHEN
;
Xin WEI
;
Liang JING
;
Chaorong SUN
;
Songhao HU
;
Chuanmin YANG
;
Yun YAN
- Publication Type:Journal Article
- Keywords:
Shegan heji;
Flavonoids;
Ephedrine;
Excretion;
Content determination
- From:
Herald of Medicine
2014;(8):985-987
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study absorption of shegan heji marker components in blood and their excretion in urine and feces of rats, after intragastric administration of shegan heji. Methods LC-MS/MS was used for determination of marker compounds. Rat metabolic cage technology was employed. Results Excretion of marker components were completed 24 hours after administration. Conclusion Ephedrine can be excreted from rats within 24 hours. The possibility of mutual transformation of flavonoids exists in the body. Taking shegan heji will not cause accumulation of ephedrine and flavonoids in the body.
