Comparative analysis of blood glucose changes of different strains of mice under food and/or water deprivation
10.7644/j.issn.1674-9960.2014.07.015
- VernacularTitle:不同品系小鼠在禁食和（或）禁水情况下血糖变化特点的比较分析
- Author:
Ruixue WANG
;
Weiguang LI
;
Liu YANG
;
Chenggang ZHANG
- Publication Type:Journal Article
- Keywords:
mouse;
blood glucose;
water deprivation;
food deprivation
- From:Military Medical Sciences
2014;(7):532-534
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide reference on the difference in blood glucose metabolism between different mouse strains by comparing blood glucose changes under food and /or water deprivation.Methods C57BL/6J mice, BALB/c mice,and ICR mice used in this study were divided into four groups:control group, food deprivation group, water depriva-tion group and food &water deprivation group .Their blood glucose was measured within 12 hours under various stresses . Results and Conclusion There are different blood glucose regulation patterns in different mice strains .The blood glucose level of C57BL/6J mice is usually higher than that of the BALB/c and ICR mice, while the of blood glucose level BALB/c mice stays relatively stable , and the ICR mice have the widest range of blood glucose levels upon these stresses .Accord-ing to our data, the difference in blood glucose metabolism between different mouse strains should be taken into considera -tion in blood glucose related studies for proper interpretation and design of experiments .
