Protective role of lipoxins in digestive diseases
10.3969/j.issn.1000-4718.2014.07.013
- VernacularTitle:脂氧素在消化系统疾病中的保护作用
- Author:
Hongrong XU
;
Xiaoyan ZHOU
- Publication Type:Journal Article
- Keywords:
Lipoxins;
Inflammation;
Digestive diseases
- From:
Chinese Journal of Pathophysiology
2014;(7):1223-1227
- CountryChina
- Language:Chinese
-
Abstract:
Lipoxins, metabolites of arachidonic acid , are a strong“braking signal” towards inflammatory reac-tion.Due to their anti-inflammatory and pro-resolving properties , lipoxins have emerged to be the central targets in the re-search on inflammation .The present article reviews the research advances of synthesis , biological effects and the protective role of lipoxins in the diseases of liver , pancreas , stomach and colorectum , thus providing a novel approach for the treat-ment of digestive diseases .