Inflammatory mediators in necrotizing enterocolitis
10.3760/cma.j.issn.1673-4408.2014.05.007
- VernacularTitle:炎症介质在坏死性小肠结肠炎发病机制中的作用
- Author:
Yong ZHANG
;
Piao YE
- Publication Type:Journal Article
- Keywords:
Necrotizing enterocolitis;
Apoptosis;
Inflammatory mediator
- From:
International Journal of Pediatrics
2014;(5):476-478
- CountryChina
- Language:Chinese
-
Abstract:
Necrotizing enterocolitis ( NEC) is a common neonatal emergency and severe case. It is a se-rious threat to the neonates. Apoptotic signal transduction pathway can be classified into extrinsic apoptotic path-way,the intrinsic apoptosis pathway and endoplasmic reticulum pathways. Inflammatory mediators can induce apoptosis in intestinal epithelial cells through the three ways mentioned above. It plays an important role in the development of NEC,which might be important for the pathogenesis of NEC.
