Insulin-like growth factor-1 generation test in diagnosis and treatment of short stature
10.3760/cma.j.issn.1673-4408.2014.05.010
- VernacularTitle:胰岛素样生长因子-1生成试验在身材矮小诊治中的应用
- Author:
Ya PENG
;
Baosheng YU
- Publication Type:Journal Article
- Keywords:
Insulin-like growth factor-1 generation test;
Short stature;
Children
- From:
International Journal of Pediatrics
2014;(5):485-488
- CountryChina
- Language:Chinese
-
Abstract:
Short stature accounts for a large proportion of endocrine diseases in children,with a complex and cross-cutting etiology. It is one of the risk factors for physical and psychological problems in children,and needs proper diagnosis and timely treatment. The insulin-like growth factor-1 ( IGF-1 ) generation test is via re-combinant human growth hormone(rhGH)stimulating peripheral target cells to secrete IGF-1. The effects of rh-GH stimulation are then evaluated according to the responsiveness of IGF-1,which is not only helpful for further determination of clinical classification of short stature,but also for therapy assessment of rhGH in time and a-chievement of personalized treatment.
