The prospect of cytochrome P450 in tumor laboratory diagnosis and personalized medicine
10.3760/cma.j.issn.1009-9158.2014.09.005
- VernacularTitle:细胞色素 P450在肿瘤的实验室诊断及个体化医疗中的价值
- Author:
Hongyan CHAI
;
Siwei LI
;
Jiancheng TU
- Publication Type:Journal Article
- Keywords:
Cytochrome p-450 enzyme system;
Neoplasms;
Individualized medicine;
Polymorphism,genetic;
Tumor markers,biological
- From:
Chinese Journal of Laboratory Medicine
2014;(9):657-660
- CountryChina
- Language:Chinese
-
Abstract:
Cytochrome P450 is a superfamily of metabolic enzymes and many of its members show tight correlation to the development of a variety of tumors.Cytochrome P450s are becoming novel research targets for personalized diagnosis and treatment because of its specialized enzymatic activity.This paper reviews the research progress and development of the cytochrome P 450 family in cancer field ,introduces the applications of cytochrome P 450 in clinical diagnosis and personalized medicine , looks into prospect research and application trend.
