Progress of GP73 as a new tumor marker for clinical application
10.3760/cma.j.issn.1009-9158.2014.09.006
- VernacularTitle:肿瘤新型标志物高尔基体蛋白73的临床应用
- Author:
Qiwen LI
;
Zhiyang LI
;
Jin SI
- Publication Type:Journal Article
- Keywords:
Membrane proteins;
Tumor markers,biological;
Liver neoplasms;
Prostatic neoplasms;
Lung neoplasms
- From:
Chinese Journal of Laboratory Medicine
2014;(9):661-664
- CountryChina
- Language:Chinese
-
Abstract:
Golgi protein 73, a novel Golgi-localized transmembrane glycoprotein , is normally expressed in biliary epithelial cells of human tissues.Researches show that GP73 is overexpressed in many tumor tissues, such as hepatocellular carcinoma , prostate cancer, lung adenocarcinoma, renal cell cancer, and so on, which may play on important role in cancer diagnosis as a novel tumor marker.