Advances of long noncoding RNA in primary liver cancer
10.3760/cma.j.issn.1009-9158.2014.09.007
- VernacularTitle:长链非编码 RN A在原发性肝癌中的临床应用
- Author:
Tingyu REN
;
Lei ZHENG
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
RNA,long noncoding
- From:
Chinese Journal of Laboratory Medicine
2014;(9):665-668
- CountryChina
- Language:Chinese
-
Abstract:
LncRNAs( long noncoding RNAs ) can be defined as RNA transcrips longer than 200nt without protein coding capacity , which play vital roles in various aspects of gene expression regulation.Recent investigations showed aberrant expression of many lncRNAs in primary liver cancer , indicating their important roles in tumorigenesis and development of liver cancer.This review focuses on the biological functions of lncRNAs and their involvements in primary liver cancer.
