The progress of induced pluripotent stem cells in neural developmental diseases
10.3760/cma.j.issn.1673-4408.2014.05.001
- VernacularTitle:诱导性多能干细胞在儿童神经系统疾病中的应用
- Author:
Xiaonan DU
;
Yi WANG
- Publication Type:Journal Article
- Keywords:
Induced pluripotent stem cell;
Nerve cell;
Pediatrics;
Neural developmental disease
- From:
International Journal of Pediatrics
2014;(5):455-457
- CountryChina
- Language:Chinese
-
Abstract:
Induced pluripotent stem cell ( iPS cell ) , similar to embryonic stem cell, can be repro-grammed to the pluripotent state by ectopic expression of specific transcription factors. The iPS cells have pluri-potency and can be induced into neuron cells,which represent a promising cellular tool to study human neurode-velopmental disease,drug screening,diagnosis and personalized treatment. This article reviews the latest progress on iPS cell and its applications in neural developmental disease.
