Distribution and drug resistance of pathogens causing bloodstream infec-tion in a general intensive care unit
10.3969/j.issn.1671-9638.2014.09.012
- VernacularTitle:综合 ICU 血流感染病原菌分布及耐药性分析
- Author:
Jie GONG
;
Weiquan HAN
- Publication Type:Journal Article
- Keywords:
intensive care unit;
bacteremia;
septicemia;
bloodstream infection;
healthcare-associated infection;
pathogen;
drug resistance,microbial;
drug-resistant bacteria
- From:
Chinese Journal of Infection Control
2014;(9):560-562
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distribution and drug resistance of pathogens causing bloodstream infection in patients in a general intensive care unit (GICU),and provide reference for the prevention of bloodstream infection and rational use of antimicrobial agents.Methods From January 2011 to December 2013,clinical data of patients who were diagnosed with bloodstream infection were reviewed retrospectively,detected pathogens and drug resist-ance were analyzed statistically.Results The major pathogens isolated from 385 patients with positive blood culture were gram-negative bacilli,which accounting for 62.34%;isolation rate of gram-positive cocci and fungi was 27.01 % and 10.65% respectively.The top five pathogens were Escherichia coli (18.18%),Pseudomonas aerugi-nosa (16.10%),Staphylococcus aureus (15.59%),Acinetobacter baumannii (13.25%),and Klebsiella pneumoni-ae (9.09%).The detection rate of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase negative Staphylococcus was 72.55% and 68.34% respectively.Gram-negative bacilli was most sensitive to imipen-em and amikacin (resistant rate was 0 -35.65%).Conclusion Gram-negative bacilli are the main pathogens in blood culture from GICU in this hospital,and drug-resistant rates are high.It’s important to strengthen blood cul-ture of patients with suspected septicemia,use antimicrobial agents rationally and control infection effectively.
