Tumor lysis syndrome following transarterial chemoembolization for advanced hepatocellular carcinoma:report of one case
10.3969/j.issn.1008-794X.2014.09.024
- VernacularTitle:原发性肝癌TACE术后肿瘤坏死综合征一例
- Author:
Zhongzhi JIA
;
Feng TIAN
;
Guomin JIANG
- Publication Type:Journal Article
- Keywords:
Tumor lysis syndrome;
Hepatocellular carcinoma;
Chemotherapy;
Embolization
- From:Journal of Interventional Radiology
2014;(9):835-837
- CountryChina
- Language:Chinese
-
Abstract:
Tumor lysis syndrome (TLS) results from a sudden and rapid release of nuclear and cytoplasmic degradation products from malignant cells. It is a rare complication in adult patients with solid tumors who are undergoing treatment. Herein, the authors present a case with advanced hepatocellular carcinoma (HCC) who developed TLS after transarterial chemoembolization (TACE), which was successfully treated with aggressive fluid administration, oral allopurinol and urine alkalization, hemodialysis and other supportive therapies. TLS following TACE should be suspected in HCC patients who has large and rapidly-growing lesion.
