Research progress on therapeutic agents for alcohol dependence syndrome
10.3969/j.issn.1001-1978.2014.10.001
- VernacularTitle:酒精依赖综合征治疗药物的研究进展
- Author:
Shoupeng WEI
;
Jianhui LIANG
- Publication Type:Journal Article
- Keywords:
alcohol dependence syndrome;
therapeutic agent;
rewarding pathway;
nucleus accumbens;
receptor;
dopamine
- From:
Chinese Pharmacological Bulletin
2014;(10):1333-1337
- CountryChina
- Language:Chinese
-
Abstract:
Alcohol is widely abused in contemporary social life, which has become a serious medical and social problem because it hurts human health and endangers public safety. Recent re-search has developed several active substances that can effective-ly improve or treat this syndrome via affecting the mesolimbic do-pamine nervous pathway to dampen rewarding effectiveness in-duced by ethanol. This paper reviews the progress in near-term studies of alcoholism-intervening agents, aiming at providing ref-erences for related mechanism exploration and drug development.
