Clinical application of autoimmune neurological diseases related antibodies
10.3760/cma.j.issn.1009-9158.2014.08.005
- VernacularTitle:神经系统自身免疫病相关抗体的临床应用
- Author:
Xiangjun CHEN
- Publication Type:Journal Article
- Keywords:
Autoimmune diseases of the nervous system;
Autoantibodies;
Multicenter study
- From:
Chinese Journal of Laboratory Medicine
2014;37(8):573-576
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune neurological diseases have a high morbidity and mortality,but are treatable if diagnosed earlier.Many auto-antibodies may become important laboratory biomarkers for the diagnosis,evaluating severity,prognosis,and even reflecting treatment response,of these diseases.With the development of new knowledge and diagnostic technology,there is a pending need for discovering new pathogenesis-based biomarkers with high sensitivity and specificity on autoimmune diseases of the nervous system.To fulfill this goal,the pathogenesis as well as translational studies in autoimmune diseases of the nervous system are highly warranted.Multi-center randomized double-blinded clinical trials are also necessary to appropriately evaluate the clinical value of these auto-antibodies.W henever possible,these validated autoantibody assays are readily encouraged to perform and popularize these methods in clinical practice.
