Study on the antioxidation activity and resistance of lipid peroxidation of panax notoginseng flower total saponins
10.3760/cma.j.issn.1673-4246.2014.10.010
- VernacularTitle:三七花总皂苷清除活性氧自由基及抗脂质过氧化作用研究谢云峰谢集照龙盛京邱莉李映新张莹
- Author:
Yunfeng XIE
;
Jizhao XIE
;
Shengjing LONG
;
Li QIU
;
Yingxin LI
;
Ying ZHANG
- Publication Type:Journal Article
- Keywords:
Panax notoginseng flower total asaponins;
Macroporous resin;
Purification;
Hydroxy radical;
Lipid peroxidation
- From:
International Journal of Traditional Chinese Medicine
2014;(10):899-901
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antioxidation activity and resistance of lipid peroxidation of panax notoginseng flower total saponins.Methods The panax notoginseng flower buds were extracted with ethanol. The hydroxyl free radical(?OH), 1,1-diphenyl-2-picrythydrazyl radical(DPPH)clearing rate and resistance of lipid peroxidation of rat liver induced by Fe2+-cysteine were determined by spectrophotometry. Results Half clearance of hydroxyl free radical and DPPH. by panax notoginseng flower total saponin was 0.035 mg/ml and 0.094 mg/ml, the maximum inhibition rate of lipid peroxidation of rat liver induced by Fe2+-cysteine was 89.31%, therefore moderate concentration of extracts had a strong inhibitory effect on lipid peroxidation. Conclusions Panax notoginseng flower total saponins have antioxidant activity and resistance of lipid peroxidation.
