Optimization of Extraction Technology of Xiaoyan Granules by Orthogonal Test
- VernacularTitle:正交试验法优选消炎颗粒提取工艺
- Author:
Jixi QIU
;
Zhenwei ZHANG
;
Yuanyuan LI
;
Lei SHI
- Publication Type:Journal Article
- Keywords:
Orthogonal test;
Xiaoyan granules;
Extraction technology;
HPLC
- From:
China Pharmacist
2014;(9):1478-1480
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction process of Xiaoyan granules. Methods:The extraction process was optimized by orthogonal test with water volume, extraction times and extraction duration as the influencing factors. The dry extract rate and esculetin content were used as the evaluation indices. The dry extract rate was determined by drying method, and esculetin was determined by HPLC. Results:The optimal extraction conditions were as follows:water was 8 times of the medicinal materials, the decoction duration was 1. 5h with 3 extraction times. Conclusion:The optimized process of Xiaoyan granules is feasible and convenient,and the granules are qualified and stable.
