The clinical efficacy of Fuzheng Huayu Capsule in liver cirrhosis decompensated and the impact on quality of life
10.3760/cma.j.issn.1008-6706.2014.18.008
- VernacularTitle:扶正化瘀胶囊治疗肝炎后肝硬化代偿期疗效观察及对患者生存质量的影响
- Author:
Jianmin ZHANG
- Publication Type:Journal Article
- Keywords:
Fuzheng Huayu Capsule;
hepatitis;
cirrhosis;
decompensation;
quality of life
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(18):2739-2741
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of Fuzheng Huayu Capsule in the treatment of liver cirrhosis (decompensated) and its impact on quality of life in patients with TCM therapy research.Methods 160 cases of liver cirrhosis (decompensated) patients were chosen as research subjects.They were divided into experimental groupand control group according to random number table.Both groups used routine liver antiviral therapy,the experimental group was given Fuzhenghuayu tablets therapy,the control group only received conventional therapy.After 6 months of treatment,and treatment for the two groups of patients were evaluated quality of life conditions.Results Compared with before treatment,HA,LN,PC Ⅲ,Ⅳ-C of the indicators were significantly decreased,and the difference was statistically significant (t =10.89,15.88,10.42,12.38,4.41,9.27,4.97,6.55,all P ＜ 0.05).After the two groups of patients for the treatment of fibrotic indicators analysis found more significant decline in the observation group,the difference was statistically significant (t =5.32,3.88,5.25,5.01,all P ＜ 0.05).2 Compared with before treatment,ALT,AST levels of the two groups were significantly decreased,the difference had statistically significant (t =2.02,17.87,2.62,7.96,all P ＜0.05).for two groups of patients was compared with that total efficiency (87.50％ vs 66.25 ％),the difference was statistically significant (x2 =10.16,P ＜ 0.05).Compared with pre-treatment,two patients in the field of physiology,psychology field,the field of social relations,environmental areas and total score was significantly higher,the difference was statistically significant (t =13.94,12.37,11.12,10.71,16.45,8.60,6.54,8.35,4.86,8.04,all P ＜ 0.05) ; The two groups of patients after treatment compare the scores and scores found in the observation group was significantly more elevated,compared with the control group,the difference was statistically significant (t =4.97,3.81,4.98,2.56,5.05,all P ＜ 0.05).Conclusion In the treatment of hepatitis cirrhosis,Fuzheng Huayu Capsule can significantly improve the degree of liver fibrosis,improve the quality of life of patients and improve clinical outcomes.
