Correlation analysis of P, IFN-γ level of artificial insemination during pregnancy and pregnancy outcome
10.3760/cma.j.issn.1008-6706.2014.18.007
- VernacularTitle:人工授精妊娠期孕酮、γ-干扰素水平与妊娠结局的相关性分析
- Author:
Honglian YAN
;
Wei LIAN
;
Bing LIN
;
Shuntian GUO
;
Xiuli HUANG
;
Jia LIU
- Publication Type:Journal Article
- Keywords:
Artificial insemination during pregnancy;
P;
IFN-γ;
pregnancy outcome;
correlation analysis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(18):2736-2738
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of P,IFN-γlevel of artificial insemination during pregnancy and pregnancy outcome.Methods 468 patients with infertility were done artificial insemination treatment cycles.The dydrogesterone were taken orally after surgery to luteal support.The blood P and IFN-γlevel of 54 patients with pregnant were observed.Results The correlation analysis of P,IFN-γ level of normal pregnancy group showed that the P level was negatively correlated with IFN-γlevel (r =-0.594,P ＜ 0.05).In the biochemical pregnancy group,the P level was decreased from the ninth days begin,and compared with the normal pregnancy group,the difference was significant(t =12.319,P ＜0.05).In the abortion group,the P level was decreased from the sixteenth days begin,and compared with the normal pregnancy group,the difference was significant (t =7.663,19.315,all P ＜0.05).Compared with the normal pregnancy group,the IFN-γ level of the biochemical pregnancy group and abortion group was significantly increased,the difference was significant (P ＜ 0.05).Conclusion The use of luteal support methods to raise the level of P in vivo has a positive effect on the prevention of biochemical pregnancy and spontaneous abortion,and monitoring the blood P and IFN-γlevel after artificial insemination can predict the prognosis of patients.
