The clinical significance of plasma LP (a),Hcy,hs-CRP and cTnI concentrations determination in patients with acute myocardial infraction
10.3969/j.issn.1673-4130.2014.18.019
- VernacularTitle:急性心肌梗死患者血浆LP（a）Hcyhs-CRP和cTnI水平检测的临床意义
- Author:
Guoxin XU
;
Fang WANG
;
Yongqing YANG
- Publication Type:Journal Article
- Keywords:
acute myocardial infraction;
lipoprotein(a);
homocysteine;
high sensitive C-reaction protein;
cardiac tropo-nin I
- From:
International Journal of Laboratory Medicine
2014;(18):2466-2468
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of plasma LP (a) ,Hcy ,hs-CRP and cTnI concentrations in patients with AMI .Methods Plasma LP(a) ,Hcy ,hs-CRP and cTnI concentrations of 162 patients with AMI and 165 healthy people recrui-ted as control group were determined .Immunofluorescent dry quantitative method and electro-chemiluminescence immunoassay were used in the determination ,and statistical analysis were used in data comparison .Results Before treatment ,the plasma LP(a) , Hcy ,hs-CRP and cTnI concentrations in 162 AMI patients were significantly higher than those in control group (P<0 .01) .After treatment ,the plasma hs-CRP concentrations in 97 improved patients returned to normal (t=1 .586 ,P>0 .05) ,but the plasma cTnI concentrations significantly decreased (t=3 .322 ,P<0 .01) .The plasma Hcy ,hs-CRP and cTnI concentrations in 36 died patients were significantly higher(P<0 .01) .Conclusion Plasma LP(a) ,Hcy ,hs-CRP and cTnI determination were valuable for the diagno-sis of AMI patients ,the most valuable indicators for patient prognosis and follow-up were plasma hs-CRP and cTnI .
