Progress in molecular prognostic biomarkers of castration-resistant prostate cancer
10.3969/j.issn.1000-8179.20140605
- VernacularTitle:去势难治性前列腺癌分子预后标志物研究进展
- Author:
Haitao WANG
;
Bin MENG
- Publication Type:Journal Article
- Keywords:
castration resistant prostate cancer;
molecular markers;
prognosis;
individualized treatment
- From:
Chinese Journal of Clinical Oncology
2014;(15):1003-1006
- CountryChina
- Language:Chinese
-
Abstract:
Prostate cancer is one of the most common malignant tumors among males, and nearly all patients will inevitably de-velop castration-resistant prostate cancer (CRPC). The prognosis of CRPC patients is very poor. How to implement the individualized treatment plan with minimal side effects and optimum benefit as well as how to prolong the patients' lives have recently become impor-tant issues. Current staging and grading systems fail to provide accurate prognoses of most CRPC, which have complicated biological behaviors. Over the past few years, a host of tumor molecular markers have been discovered and can provide prognostic information for CRPC. This review summarizes the molecular prognostic biomarkers that affect the prognosis of CRPC.
