EML4-ALK fusion gene in tumor
10.3760/cma.j.issn.1673-422X.2014.07.002
- VernacularTitle:EML4-ALK融合基因在肿瘤中的研究进展
- Author:
Yinan GUO
;
Wentao YUE
- Publication Type:Journal Article
- Keywords:
Neoplasms;
EML4-ALKfusiongene
- From:
Journal of International Oncology
2014;(7):484-487
- CountryChina
- Language:Chinese
-
Abstract:
EML4-ALKfusiongeneisoneofthenoveltargetsinthetherapyoflungcancer,whichcan be detected in several kinds of tumors.A specific ALK inhibitor has been shown to exert anti-tumor effects in non-small cell lung cancer with the EML4-ALK fusion gene.Correlative study between EML4-ALK gene fusion and EGFR-Kras mutations might cast new insight on the tumor target therapy.
