New applications of apolipoprotein A1 in ovarian cancer
10.3760/cma.j.issn.1673-422X.2014.07.015
- VernacularTitle:载脂蛋白A1在卵巢癌中的新应用
- Author:
Junjun ZHANG
;
Jian SHI
- Publication Type:Journal Article
- Keywords:
Ovarianneoplasms;
Tumormarkers,biological;
ApolipoproteinA1
- From:
Journal of International Oncology
2014;(7):529-533
- CountryChina
- Language:Chinese
-
Abstract:
ApolipoptoteinA1isthemaincomponentofhigh-densitylipoproteincholesterolintheplas-ma,which plays an important role in the lipid transportation and metabolism.It is closely related with cardio-vascular disease,liver disease,hereditary amyloidosis and so on.CA1 25 ,as an important biomarker,has been widely used for the diagnosis and monitoring treatment of ovarian cancer.Improved sensitivity and specificity of diagnosis are obtained when it is combined with other tumor markers,especially CA1 25 .As reported recently, it also is related with the generation,progress and prognosis of ovarian cancer.It has been promising to be a new kind of treatment.
