Application research of MR diffusion tensor imaging in diagnosis traumatic axonal injury
10.3760/cma.j.issn.1008-1372.2014.07.015
- VernacularTitle:磁共振扩散张量成像对创伤性轴索损伤的诊断应用研究
- Author:
Wenbin LIANG
;
Zhengwei LIU
;
Jiyin RUAN
;
Mingwu LOU
;
Yunxia SHEN
- Publication Type:Journal Article
- Keywords:
Wounds and injuries/diagnosis;
Axons;
Magnetic resonance imaging;
Anisotropy
- From:
Journal of Chinese Physician
2014;(7):909-912
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of MR diffusion tensor imaging ( DTI) in diagnosis of traumatic Axonal injury ( TAI) .Methods Twenty nine patients with traumatic brain injury ( TBI) and matched 22 control subjects were performed with DTI . Fractional anisotropy ( FA) was calculated from semioval center , corpus callosum , internal capsule and pons of controls and TBI pa-tients.According to Glasgow Score (GCS), TBI patients were divided into mild group (GCS≥13) and moderate-severe group (GCS≤12), each group compared with control group in FA value .The correlation between FA values in different regions and GCS score were analyzed in DTI group .Results FA value of semioval center was decreased in mild DTI group ( P <0.01 ) .FA values of semio-val center , corpus callosum , and internal capsule were decreased in moderate-severe DTI group ( P <0.05 ) .The FA values in semio-val center , corpus callosum , and internal capsule were positively correlated with GCS score in TBI group ( P <0.05 ) .Conclusions DTI is sensitive to detect the traumatic axonal injury??Changes of FA value in ROIs can access the severity of axonal injury ?? which ishelpful for diagnosis earlier and improving prognosis.
