Histological observation of rat's parotid gland after ligation and reopening of the main duct
10.3969/j.issn.1001-3733.2014.04.05
- VernacularTitle:大鼠腮腺主导管结扎及再通后的组织学观察
- Author:
Yulong MAO
;
Jinhua ZUO
;
Weiwei ZHANG
- Publication Type:Journal Article
- Keywords:
Parotid gland;
Regeneration;
Atrophy;
Morphometry
- From:
Journal of Practical Stomatology
2014;(4):469-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the histological changes of parotid gland after ligation and reopening of the main duct.Meth-ods:The right parotid main duct was ligated for 14 days and then reopened,the specimen were harvested at day 0,1,3,5,7,10,14 and 21 after reopening(n=5 )respectively.By HE staining and Morphology measurement,the morphological and volume fraction changes of acinus,duct and mesenchyma were observed and measured.Results:The parotid gland atrophied significantly 14 days af-ter the duct ligation.From day 3 after duct reopening,the acinar volume fraction continued to increase,both the duct and the mesen-chymal tissue volume fraction continued to decrease significantly(P<0.05).After 14 days of duct reopening,there was no signifi-cant difference in volume fraction of acinar,duct and mesenchyma,compared with those of normal control group(P>0.05).Conclu-sion:After reopening of the ligated main duct the atrophied parotid gland is able to regenerate to be normal.
