Progress of streptococcus pneumoniae infection and immunity
10.3760/cma.j.issn.1673-4408.2014.04.008
- VernacularTitle:肺炎链球菌的感染与免疫研究进展
- Author:
Bing ZHAO
;
Jiahua PAN
- Publication Type:Journal Article
- Keywords:
Streptococcus pneumoniae;
Pneumococcal pneumonia;
Pneumococcal disease;
Immunity
- From:
International Journal of Pediatrics
2014;(4):365-368
- CountryChina
- Language:Chinese
-
Abstract:
Streptococcus pneumoniae( SP) is the leading pathogenic bacteria of invasive bacterial infec-tions in children. It can cause some life-threatening diseases such as pneumonia,meningitis and sepsis. Strepto-coccus pneumoniae frequently colonizes the upper respiratory tract. It is essential to know the host immune re-sponse during the infection. This paper reviews antigenic structure of SP,pneumococcal conjugate vaccine and pneumococcal virulence factors,especially focuses on the immune response including the effect of innate immu-nity,macrophage,neutrophil and T-cell.
