Analysis of bacterial distribution and antibiotic resistance in bone and joint purulent infection of elderly patients
- VernacularTitle:骨与关节化脓性感染的老年患者菌群分布及抗生素耐药性分析
- Author:
Ou SHUANG
;
Jianmin ZHOU
;
Jian LI
;
Xianyu ZHANG
;
Yuehua WANG
;
Ye HUANG
- Publication Type:Journal Article
- Keywords:
bone and joint;
purulent infection;
pathogens;
drug resistance
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;37(4):108-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the distribution of pathogens causing bone and joint purulent infections and the bacterial resistance to antibiotics,and to provide reference of clinical antibiotic therapy.Methods A total of 514 patients who had bone and joint purulent infections in Department of Orthopedics of Shangrao People’s Hospital from Jan 2009 to Jun 2013 were retrospectively analyzed. Results 296 strains of Gram-negative bacteria were isolated,the infection rate was 47.2%,among which 296 strains of Escherichia coli were the most common infection pathogen,the infection rate was 15.6%,followed by Acinetobacter baumannii,Pseudomonas aeruginosa,and the infection rates were 11.8%,11.3%.331 strains of Gram-positive bacteria were isolated,the infection rate was 52.8%.Staphylococcus epidermidis,Staphylococcus aureus,were the common infection pathogens,following the infection rates were 21.5%,13.7%.Gram-negative bacteria had the highest sensitivity to imipenem,while Gram-positive bacteria had sensitivity to vancomycin.Conclusion Gram-positive bacteria is the main pathogens with bone and joint purulent infections.Selection of antibiotics according to the drug sensitive test has important clinical significance.
