Studies on optimizing extraction technology of Euphorbia hirta L.by central composite design-response surface methodology
- VernacularTitle:星点设计-效应面法优化飞扬草提取工艺研究
- Author:
Li TAO
;
Xuecheng CAO
;
Jinhui ZHOU
- Publication Type:Journal Article
- Keywords:
Euphorbia hirta L.;
central composite design-response surface thodology;
Quercitroside;
ultrasonic extraction
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;37(4):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction process of Euphorbia hirta L.by Central composite design/response surface methodology with ethanol by the ultrasonic extraction technology.Methods Based on the single factor experiment and central composite design-response surface methodology,the content of quercitroside was regarded as evaluation index,select ethanol concentration,extraction time,and solid-liquid ratio as three evaluation factors to achieve the purpose. Results The results indicated that the optimal extraction process was obtained as follows:10 times the amount of 60% ethanol under ultrasound for 2 times,50 min each;the average content of the quercitroside was 2.39 mg/g.Conclusion The method to optimize the extraction process is simple and reasonable.
