Continuous blood purification and acute kidney injury in newborns
10.3760/cma.j.issn.1673-4408.2014.04.028
- VernacularTitle:连续性血液净化与新生儿急性肾损伤
- Author:
Cheng CAI
;
Gang QIU
- Publication Type:Journal Article
- Keywords:
Kidney injury;
Blood purification;
Neonates;
Treatment
- From:
International Journal of Pediatrics
2014;(4):434-437
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury ( AKI) in newborns is one of neonatal critical disease,the incidence of AKI is 23%and the mortality is 25%~50%in neonatal intensive care unit (NICU).AKI in newborns is ab-normal renal function due to many various unfavorable factors,such as neonatal asphyxia,low blood volume, shock,hypoxia,hemolysis,low temperature,the clinical manifestations are oliguria or anuria,electrolyte disturb-ance,acid-base imbalance, high concentrations of metabolites in plasma and renal excretion ( urea, creatinine etc.) .At present,there are no effective prevention measures.In recent years,with the progress of blood purifica-tion technology,continuous blood purification ( CBP) has been used from AKI in children to AKI in newborns. Because of the neonatal hemodynamic instability and blood characteristics of small capacity, the application of CBP in the neonatal AKI still faces many problems.The paper summarizes high risk factors and diagnostic crite-ria of AKI in newborns,related problems of neonatal CBP treatment.
