Investigate the improvement of quality standard on eight-positive particles
- VernacularTitle:八正颗粒质量标准的改善研究
- Author:
Wangpeng SHENG
- Publication Type:Journal Article
- Keywords:
eight-positive particles;
gardenin;
emodin;
chrysophanol;
quality standards
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;37(4):164-168
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the content determination of eight-positive particles,and better control drug quality.Methods Gardenin, emodin and chrysophanol of eight-positive particles were determined by HPLC.Revised content determination standards and improved the standards of quality control. Results The revised content determinations of gardenin, emodin and chrysophanol were simple and feasible, and had high sensitivity.Conclusion Unification the quality standards of eight positive granules,the standards provide the basis for standardizing the market of eight-positive particles.