Transcatheter aortic valve implantation:the preliminary experience from West China Hospital

Mao Chen; Yuan Feng; Hong Tang; Xin Wei; Zhengang Zhao; Yuanning XU; Yanbiao Liao; Dejia Huang

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Transcatheter aortic valve implantation:the preliminary experience from West China Hospital

VernacularTitle:经导管主动脉瓣植入术治疗重度主动脉瓣狭窄患者的初步经验
Author: Mao CHEN ; Yuan FENG ; Hong TANG ; Xin WEI ; Zhengang ZHAO ; Yuanning XU ; Yanbiao LIAO ; Dejia HUANG
Publication Type:Journal Article
Keywords: Aortic stenosis; Bicuspid aortic valve; Transcatheter aortic valve implantation
From: Chinese Journal of Interventional Cardiology 2014;(9):558-562
CountryChina
Language:Chinese
Abstract: Objective To discuss the preliminary experience of transcatheter aortic valve implatantion in patients with severe aortic valve stenosis. Methods The baseline characteristics, hemodynamic changes and clinical outcomes of the patients received TAVI in our institution were analyzed. Results A total of 36 patients underwent TAVI between April 2012 and March 2014. The mean age was (73.4±8.7) years and 24 (66.7%) of them were men. The mean logistic EuroSCORE was (20.6±9.9)%. 25(70%) patients had bicuspid aortic valves. TAVI was successful in 35 patients (97.2%) and valve-in-valve implantation was required in 4 (11.1%) of them. After the procedure, the mean aortic-valve gradient reduced to (10.5±5.7) mmHg. In 2 patients (5.6%), there was marginal moderate periprosthetic leak. At 30 days, the survival rate was 97.2%. Two patients (5.6%) developed who later showed fuel recovery, without significant sequela. Permanent pacemakers were implanted in 10 patients (27.8%) due to the onset of third-degree atrioventricular block after TAVI. To date, the median follow-up duration has exceeded 323 days. 2 patients died of cancer on 374 days and 680 days after TAVI, respectively. Conclusions TAVI is feasible, safe and effective in treating severe stenosis of bicuspid as well as tricuspid aortic valve in selected Chinese patients unsuitable for surgery.