Analysis and treatment of intra-abdominal infectious after pancreatic surgery
10.3760/cma.j.issn.1007-8118.2014.07.011
- VernacularTitle:胰腺术后腹腔感染的分析及治疗
- Author:
Junfeng ZHANG
;
Yongwei SUN
;
Rong HUA
;
Wei LIU
;
Yanmiao HUO
;
Dejun LIU
;
Jiao LI
- Publication Type:Journal Article
- Keywords:
Pancreas surgery;
Intra-abdominal infections;
Pancreatic fistula;
Bacterial culture
- From:
Chinese Journal of Hepatobiliary Surgery
2014;20(7):519-523
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the bacterial types and their drug resistance in intra-abdominal infections after pancreatic surgery,and to evaluate the appropriate treatment measures.Methods 113 patients who underwent pancreatic surgery from Jan 2012 to Dec 2012 in our hospital were included into this study.The drainage liquid from the surgical sites were collected for bacterial culture and drug susceptibility tests.Results The incidence of intra-abdominal infections was 39.8％ (45/113).There were 54 pathogenic strains of bacteria isolated,including 49 strains of gram-negative bacteria (90.7％),4 strains of gram-positive bacteria (7.4％),and 1 strain of fungus (1.9％).The top three pathogens were Pseudomonas aeruginosa (50.0％),Acinetobacter baumannii (14.8％) and Singular deformation bacteria (1 1.1％).Most gram-negative bacteria were sensitive to Polymyxin B and Aminoglycoside antibiotics (＞ 70％),but they were resistant to Imipenem and Cephalosporin which were commonly administered.Pancreatic fistula was closely related to intra-abdominal infections.Concluusions A gram-negative bacteria,Pseudomonas aeruginosa,was the predominant organism in intra-abdominal infections after pancreatic surgery in our hospital.The situation of drug-resistance was still severe.More effective measures should be taken to prevent growth of resistant strains such as using antibiotics according to drug sensitivity and avoiding empirical single use of broad-spectrum antibiotics.Pancreatic fistula commonly led to intra-abdominal infections.
