Value of real time shear wave elastography in differential diagnosis of benign and malignant breast lesions
10.3969/j.issn.1671-8348.2014.25.003
- VernacularTitle:实时剪切波弹性成像对乳腺病灶良恶性的鉴别诊断价值
- Author:
Xue LIU
;
Ying DU
;
Yanfeng YAO
;
Dongzhu ZHANG
;
Mengfei ZHANG
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
diagnosis,differential;
elasticity imaging techniques;
ultrasonography,Doppler,color
- From:
Chongqing Medicine
2014;(25):3272-3274
- CountryChina
- Language:Chinese
-
Abstract:
Objective To use the real-time shear wave elastography(SWE)to detect the elasticmodulus values of different breast lesions,and to assess its application value in differential diagnosis of benign and malignant breast lesions.Methods SWE was per-formed in 71 breast lesions from 63 pathologically confirmed patients.The maximum,minimum and mean elasticmodulus values in breast lesions were detected and the ROC curves were used to determine the optimal diagnostic cut off value.Results Among 7 1 le-sions,48 cases were benign lesions and 23 cases were malignant lesions.The diagnostic accuracy and Youden index of the ordinary ultrasound were 77.5% and 0.55 respectively.The maximum,minimum and mean elasticity values for malignant lesions were (106.7±37.9),(23.7±6.4),(44.8±6.6)kPa respectively,whereas which for benign lesions were(42.7±14.6),(17.2±6.3), (29.4±8.0)kPa respectively.The maximum,minimum and mean elastic values had statistically significant differences between be-nign and malignant lesions(P<0.05).The areas under the curve(AUC)of the maximum,minimum and mean elastic values were 0.963,0.798 and 0.914 respectively.Taking 78.1 kPa as the threshold of the maximum elasticity value,the sensitivity was 82.6%and the specificity was 95.8%.Taking 37.6 kPa as the threshold of the mean elasticity value,the sensitivity was 87.0% and the specificity was 83.3%.Conclusion SWE provides a new way for the differential diagnosis of benign and malignant breast lesions, and the maximum and mean elastic value can be used as the diagnostic evidence for differentiating benign and malignant breast le-sions.
