Optimization of Ultrasonic Extraction of Asperosaponin VI from Dipsaci Radix by Response Surface Methodology

VernacularTitle:响应面法优化续断中川续断皂苷VI的超声提取工艺
Author: Hailin ZHU ; Zhaoqing MENG ; Gang DING ; Wei XIAO
Publication Type:Journal Article
Keywords: Dipsaci Radix; ultrasonic; response surface methodology; technology optimization
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(8):1777-1783
CountryChina
Language:Chinese
Abstract: This study was aimed to optimize extraction technology of Asperosaponin VI from Dipsaci Radix by re-sponse surface methodology (RSM). A single-factor test and Box-Behnken design (BBD) were employed to optimize three extraction variables, including extraction time (A), ethanol concentration (B), and the ratio of ethanol to materi-al (C). The transfer rate of Asperosaponin VI was used as the evaluation index. The results showed that the optimized conditions were A of 33.13 min, B of 51.58 %, C of 23.39 mL·g-1. Under these conditions, the transfer rate was 88.39 ± 0.212% (n = 3), which was well matched with the predicted transfer rate. It was concluded that RSM can be used for extraction optimization of ultrasonic extraction process for Asperosaponin VI. This method had certain prac-tical values.